Siping Zhang , Xiaofang Lin

Tropical Animal Medicine Center, Hainan Institute of Tropical Agricultural Resources, Sanya, 572024, China
Author    Correspondence author
Animal Molecular Breeding, 2024, Vol. 14, No. 1   doi: 10.5376/amb.2024.14.0006
Received: 20 Nov., 2023    Accepted: 02 Jan., 2024    Published: 26 Jan., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Zhang S.P., and Lin X.F., 2024, Whole-genome association analysis in revealing the application of genetic factors affecting livestock production traits, Animal Molecular Breeding, 14(1): 45-53 (doi: 10.5376/amb.2024.14.0006)

This study reviews the application of whole-genome association analysis in revealing genetic factors affecting livestock production traits. With the continuous development of biotechnology and genomics, whole-genome association analysis has gradually received attention as a powerful genetic research tool. This method detects associations between a large number of genetic markers and traits of interest, revealing the genetic basis of livestock production traits and providing a scientific basis for breeding and genetic improvement. This study first introduces the definition and classification of livestock production traits, as well as their genetic background and influencing factors. Next, an overview of the principles and methods of whole-genome association analysis is provided, along with a comparison of the advantages and disadvantages of traditional genetic research methods and whole-genome association analysis. Subsequently, through typical case analysis, the application and technological progress of whole-genome association analysis in the study of livestock production traits are elaborated in detail. Further discussion includes key genes and genetic markers identified through this method, as well as their practical applications in livestock genetic improvement. Finally, the importance of whole-genome association analysis in deciphering the genetic basis of livestock production traits is summarized, and the potential application value of it in the sustainable development of animal husbandry is discussed.

Whole-genome association analysis; Livestock production traits; Genetic factors; Breeding; Genetic improvement