Yanlin Wang , Qiqi Zhou , Jia Chen

Tropical Animal Resources Research Center, Hainan Institute of Tropical Agricultural Resources, Sanya, 572000, Hainan, China
Author    Correspondence author
Animal Molecular Breeding, 2024, Vol. 14, No. 6   doi: 10.5376/amb.2024.14.0036
Received: 03 Nov., 2024    Accepted: 05 Dec., 2024    Published: 16 Dec., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Wang Y.L., Zhou Q.Q., and Chen J., 2024, A review of gene editing technologies in poultry breeding: focus on CRISPR/Cas9, Animal Molecular Breeding, 14(6): 345-353 (doi: 10.5376/amb.2024.14.0036)

This study reviews various gene editing techniques, including CRISPR/Cas9, TALENs, and ZFNs, and emphasizes their advantages over traditional breeding. It analyzes CRISPR/Cas9 in detail, explores the use of gene editing to improve the growth, meat quality, disease resistance, and reproductive traits of poultry, reviews the ethical considerations, regulatory challenges, and safety assessments of gene edited poultry, and provides practical insights into the potential and limitations of using CRISPR/Cas9 to enhance disease resistance. Finally, it discusses future innovations in gene editing tools, integration of multi omics methods, and industry application prospects. This study aims to emphasize the transformative potential of gene editing in poultry breeding and call for ongoing research to optimize the technology and address regulatory and ethical challenges.

Poultry breeding; Gene editing; CRISPR/Cas9; TALEN; ZFN