Jun Wang , Jun Li

Animal Science Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
International Journal of Molecular Veterinary Research, 2024, Vol. 14, No. 4   
Received: 07 Jun., 2024    Accepted: 17 Jul., 2024    Published: 28 Jul., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study explores the complex relationship between gut microbiota composition and dog immune function, emphasizing the dynamic interaction between microbiota and host defense mechanisms. It deeply analyzes the factors affecting gut microbiota diversity, core microbial species and their functional roles, and compares them with other species. It reviews the mechanisms by which gut microbiota regulates immune responses, including microbial metabolites and immune signaling pathways, and evaluates probiotic, prebiotic, fecal microbiota transplantation, and dietary strategies aimed at supporting dog immune health. A case study on dogs with allergic dermatitis emphasizes the importance of gut microbiota in immune related diseases and demonstrates potential therapeutic pathways. This study identified key knowledge gaps and emphasized the necessity of standardized interventions and personalized methods based on microbiota in veterinary medicine, deepening the understanding of immune interactions between gut microbiota and potentially improving dog health and shaping the future of veterinary care.

Canine gut microbiota; Immune responses; Probiotics; Microbiota-immune crosstalk; Veterinary medicine