Xiaofang Lin

Tropical Animal Medicine Research Center, Hainan Institute of Tropical Agricultural Resources, Sanya, 572000, Hainan, China
Author    Correspondence author
International Journal of Molecular Veterinary Research, 2024, Vol. 14, No. 6   doi: 10.5376/ijmvr.2024.14.0030
Received: 12 Nov., 2024    Accepted: 13 Dec., 2024    Published: 26 Dec., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Lin X.F., 2024, Interactions between African swine fever virus and host cells: mechanisms and outcomes, International Journal of Molecular Veterinary Research, 14(6): 261-268 (doi: 10.5376/ijmvr.2024.14.0030)

This study explores the complex interactions between ASFV and host cells, with a focus on the mechanisms of virus entry and replication, as well as the cellular and systemic outcomes of infection. It emphasizes how ASFV utilizes host cell mechanisms to manipulate immune responses and induce cytopathic effects, ultimately leading to disease progression. Future research priorities, including technological advancements and global management strategies, are discussed, emphasizing the importance of comprehensive approaches to mitigate the impact of African swine fever. A case study of a regional epidemic provides insights into host response and broader impacts on pig health, emphasizing the challenges of current control measures and the necessity of innovative vaccines and treatment strategies. This review aims to deepen our understanding of the biology of African swine fever virus and provide information for developing effective control and prevention measures.

African swine fever virus (ASFV); Viral-host interactions; Immune evasion; Cytopathic effects; Disease control strategies