A Letter

Diagnosis and Treatment of Myasthenia Gravis in a Golden Retriever Dog  

Mehraj u din  Dar1 , D. B.  Patil2 , Hussain Khadim Dar1
1 Division of Veterinary Surgery and Radiology, Faculty of Veterinary Sciences & Animal Husbandry, Sher-e Kashmir University of Agricultural Sciences and Technology-Kashmir 190006, India
2 Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Anand Agricultural University, Anand, Gujarat-388001, India
Author    Correspondence author
International Journal of Molecular Zoology, 2015, Vol. 5, No. 3   doi: 10.5376/ijmz.2015.05.0003
Received: 04 Nov., 2015    Accepted: 16 Dec., 2015    Published: 20 Dec., 2015
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Dar M., Patil D.B., and Dar K.H., 2015, Diagnosis and treatment of myasthenia gravis in a Golden Retriever dog, International Journal of Molecular Zoology, 5(3): 1-3 (doi: 10.5376/ijmz.2015.05.0003)


A four years old male Golden Retriever weighing 34 kg was brought to our clinics with the complaints of exhaustion and fatigue for the past month, inability to stand on its hind legs, loss of voice and anorexia. In clinical examination, difficulty in lifting the head, pelvic limb weakness and regurgitation were observed. Lateral thoracic radiograph showed enlarged thymus gland and megaesophagus. Myasthenia gravis was suspected and 2.5 mg of Edrophonium Chloride was administered IV. A positive response was seen within 30 minutes of drug application. The disease was diagnosed as Myasthenia gravis. Treatment improved the pelvic limb weakness however the dog died after 10 days.

Myasthenia gravis; Edrophonium chloride
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