Xiao Zhu , Xiaofang Lin

Hainan Institute of Tropical Agricultural Resources, Tropical Animal Center, Sanya, 572025, China
Author    Correspondence author
International Journal of Molecular Zoology, 2024, Vol. 14, No. 1   doi: 10.5376/ijmz.2024.14.0004
Received: 04 Jan., 2024    Accepted: 13 Feb., 2024    Published: 25 Feb., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Zhu X., and Lin X.F., 2024, Review of porcine disease resistance genetic basis research based on GWAS, International Journal of Molecular Zoology, 14(1): 22-30 (doi: 10.5376/ijmz.2024.14.0004)

This study reviews the latest progress in research on the genetic basis of porcine disease resistance based on GWAS. This study first introduces the importance and challenges of porcine disease resistance to the breeding industry, as well as the history and current status of research on porcine disease resistance; Then elaborates on the role and advantages of GWAS technology in research on the genetic basis of disease resistance, including its characteristics of high-throughput, high-resolution and comprehensive detection of genetic variation; Furthermore, it focuses on the important results achieved by GWAS-based research in discovering genetic variations related to porcine disease resistance, and the impact of these variations on disease resistance. Potential influencing mechanisms of sex. This study also explores the limitations of GWAS in porcine disease resistance research, and looks at the direction and potential contributions of future research, with a view to providing more effective strategies and means for pig health management and the sustainable development of the breeding industry.

Porcine disease resistance; GWAS; Genetic basis; Genetic variation; Breeding industry