CRISPR-Cas9 Gene Editing Approach Can Alter the Social Behavior of Animals
Published:31 May2022 Source:Georgia State University
Georgia State University scientists have created gene-edited hamsters for studies of social neuroscience and have found that the biology behind social behavior may be more complex than previously thought.
A team of Georgia State University researchers led by Regents' Professor of Neuroscience H. Elliott Albers and Distinguished University Professor Kim Huhman used CRISPR-Cas9 technology to eliminate the actions of a neurochemical signaling pathway that plays a critical role in regulating social behaviors in mammals. Vasopressin and the receptor that it acts on called Avpr1a regulates social phenomena ranging from pair bonding, cooperation, and social communication to dominance and aggression.